It has good physical and mechanical properties, oil resistance, heat resistance, flame resistance, sunlight resistance, ozone resistance, acid and alkali resistance, and chemical reagent resistance. The disadvantage is poor cold resistance and storage stability. It has high tensile strength, elongation, reversible crystallinity and good adhesion. Resistance to aging and heat. Excellent oil and chemical resistance. The weather resistance and ozone aging resistance are second only to EPDM and butyl rubber. The heat resistance is equivalent to that of nitrile rubber, with decomposition temperature of 230~260 ℃, short-term resistance of 120~150 ℃, long-term use at 80~100 ℃, and certain flame retardancy. Oil resistance is second only to nitrile rubber. Good resistance to inorganic acid and alkali corrosion. Slightly poor cold resistance and poor electrical insulation. The storage stability of raw rubber is poor, resulting in "self sulfur" phenomenon. Mooney viscosity increases and raw rubber hardens.

Neoprene rubber is flexible and can maintain its shape over time, so it can be used to make padding for orthopedic support of wrist and knee. Laboratory personnel handling chemicals may use synthetic rubber gloves made of neoprene, which often have good flexibility, finger flexibility, high density and tear resistance to protect their hands from long-term chemical contact. Gloves made of neoprene can help protect the wearer's hands from hydraulic oil, gasoline, alcohol, organic acids and alkalis.