Product Description

Delivery Time:10days in case of order
Certification:KOSHER,HALAL,ISO9001，HACCP,GMP,BRC

Pharmaceutical Water Soluble Oral BCAA 611 Leucine Isoleucine Valine

Quick Detail:

PRODUCT NAME: BCAA GRANULAR--DC95(BRANCHED CHAIN AMINO ACIDS),

FORMULA: 6:1:1(50% L-LEUCINE,25%L-ISOLEUCINE,25%L-VALINE):

MAIN ESSENTIAL AMINO ACIDS

APPEARANCE: SPHERIC GRANULES

COLOR: WHITE OR OFFWHITE

SMELL: SLIGHTLY ODOUR;

TASTE: SLIGHTLY BITTER;

Description:

The branched-chain amino acids (BCAA) – leucine, isoleucine, and valine – are unique among amino acids in that they are primarily metabolized extrahepatically in skeletal muscle. 1,2In muscle, the BCAA serve as both an important energy substrate during exercise and periods of stress, and as a precursor for the synthesis of other amino acids and proteins. 3 Initial research into BCAA focused on both their anabolic effects in particular in catabolic disease states, and on their theoretical potential for preventing encephalopathy in liver failure. Accordingly, BCAA were promoted as beneficial supplements in patients suffering from such conditions. However, a number of equivocal clinical studies have resulted in a general loss of interest in BCAA as a nutritional supplement.

The BCAA exert significant influences on glutamine metabolism. 4 Glutamine is recognized as an important nutrient to many rapidly dividing cells in the body, especially in the gut and the immune system. Hence, conventional parenteral or enteral diets that are deficient in glutamine (because of its instability in solution) are associated with gut atrophy and immune deficiency. Enriching parenteral nutrition with glutamine serves to partially reverse this gut atrophy. 5 The infusion of BCAA-enriched parenteral nutrition has been found to have similar effects on the gut and is most likely serving to increase endogenous synthesis of glutamine. 5 Nonetheless, the practical application of this knowledge has never been achieved.

There is likely still to be a role for BCAA in the nutritional management of patients with catabolic disease states. This is especially so as the management of such patients is approached with combinations of both anabolic agents (e.g. growth hormone) and specific nutrients (e.g. glutamine, arginine, BCAA). This review aims to cover our current understanding of the biochemistry of BCAA, and their clinical utility in various pathological states.

Applications:

SOLID DRINK; PROTEIN BEVERAGE POWDER; TABLETS;CAPSULES; INJECTION;

Specifications:

Specification Standard Item	IN HOUSE STANDARD
Description	White to off-white Powder
Assay(Titration)	≥95%
Binder	≤5%
Leucine Content(HPLC)	45.0～55.0%
Isoleucine Content(HPLC)	22.5.～27.5%
Valine Content(HPLC)	22.5～27.5%
Bulk Density	0.25～0.45g/ml
Tapped Density	0.45～0.65g/ml
Heavy metals(Pb)	≤10ppm
Lead	≤3ppm
Cadmium	≤1ppm
Arsenic(As)	≤1ppm
Mercury	≤0.1ppm
Loss on drying	≤0.50%
Residue on ignition	≤0.5%
Total plate count	≤1000cfu/g
Yeast and Moulds	≤100cfu/g
E.Coli	Absent
Salmonella	Absent
Particle Size Range	≥80% through 20 mesh

Competitive Advantage:

1. PRODUCED BY:

ISO9001:2008 CERTIFIED COMPANY;

STAR-K KOSHER CERTIFIED COMPANY;

IFANCA HALAL CERTIFIED COMPANY;

HACCP CERTIFIED COMPANY;

GMP