Chinese Herbal Medicine Polyporus Umbellatus For Anti-Aging
Product description
Product Description
Delivery Time:1MONTH BY SEA,10DAYS BY AIR
Certification:ISO9000
Chinese Herbal Medicine Polyporus Umbellatus For Anti-Aging
Name:Polyporus Umbellatus
Moisture: 10%
Size: 5,8,10,12cm with diameter
Color: black or brown
Feature: 100% green and pesticide free
Application: Anti-Tumor Effects, Diuretic effects, Antioxidant and free-radical scavenging activity, Immune System Enhancement
Certification: ISO9000
Detailed Description:
Common names
Umbrella polypore
grifola
zhuling (or chuling, depending on the source) (chinese)
chorei
eichhase (german)
polypore en ombelle (french)
The common name zhuling refers to the sclerotium of the mushroom, while chorei is the fruiting body.
Medicinal properties
Polyporus umbellatus is a saprophytic mushroom that grows on withered beech and maple trees roots. Its sclerotium, called zhuling, is a crude drug commonly used for urological disorders in chinese medicine because of its diuretic effect (i.e. Promoting urination). A number of studies have shown that p. Umbellatus has a variety of medicinal properties, which are summarized below
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Anti-Tumor Effects
Polysaccharides extracted from the mycelial culture of p. Umbellatus and administered intraperitoneally into white mice at a dosage of 300 mg/kg inhibited the growth of sarcoma 180 and ehrlich solid cancers by 70% and 80%, respectively (ohtsuka et al., 1973).
P. Umbellatus was later reported to have antitumor effects in a japanese study (ito et al., 1976).
From the crude drug chorei, seven components named polyporusterone a, b, c, d, e, f and g, have been isolated. These compounds were cytotoxic to leukemia cells (ohsawa et al., 1992).
When combined with the chemotherapeutic agent mitomycin c, zhuling was shown to increase the lifespan of mice with tumors (you et al., 1994).
Zhuling was also shown to be useful in reducing the postoperative recurrence rate of bladder cancer. Recurrence rates were 34.9%, compared to 41.7% in the mitomycin c group, and 64.7% in the control group (yang et al., 1999). Similar results were reported in yang et al. (1994) and yang (1991).
P. Umbellatus polysaccharides can offset the immunosuppression of the supernatant from s180 cell culture, which may be mediated by down-regulating the synthesis and/or secretion of immunosuppressive substance by s180 cells (yang et al., 2004).
Ergone (ergosta-4,6,8(14),22-tetraen-3-one), an ergosterol derivative isolated from an alcohol extract of p. Umbellatus, was shown to be effective in killing various human cancer cell lines. The cytotoxic effects were greatest against the cervical and gastric carcinoma cell lines, but less so against colon and stomach cancer (lee et al., 2005).
Cachexia, characterized by loss of weight, muscle atrophy, fatigue, weakness and loss of , is a common condition arising in many human cancer patients, especially those with gastrointestinal or lung cancer. Cachexia is thought to be the most frequent cause of eventual death in such patients. The tumor secretes a compound that breaks down fatty acid tissue in the host, and uses these breakdown products to help grow new cancerous cells. One of these compounds, toxohormone-l, is a protein that also suppresses food and water intake, promoting anorexia in these patients. P. Umbellatus polysaccharides were shown to inhibit the cachexia induced by toxohormone-l (wu et al., 1997).
Diuretic effects
Zhuling was originally described in shen nong ben cao jing (the divine farmer’s materia medica classic) as having diuretic action and was used mainly for edema and dysuria (wang et al., 1964). Clinical studies have confirmed that polyporus umbellatus is an effective diuretic, without side effects, for the treatment of pyelonephritis, nephritis and urologic calculi (wang et al., 1964).
Aldosterone is a steroid hormone produced by the the adrenal gland, and it regulates sodium and potassium balance in the blood. Ergone has also been shown to have an anti-aldosteronic diuretic effect (yuan et al
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