Bimatoprost
Product description
Name | Bimatoprost |
Synonyms | (Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-ethylhept-5-enamide |
Molecular Formula | C25H37NO4 |
Molecular Weight | 415.57 |
CAS Registry Number | 155206-00-1 |
White powder
Residue on ignition≤0.1%
Heavy metals≤10ppm
Water≤0.5%
Related substances
15 |3 -bimatopros≤0.2%
15-Keto derivative≤0.2%
5,6-trans Isomer≤0.2%
Any other impurity≤0.1 %
Total other impurities≤0.5 %
N-Hexane≤0.029 %
Ethanol≤0.5 %
Ether≤0.5 %
Acetic ether ≤0.5 %
Assay(HPLC)99.0-101.0%
Bimatoprost is a synthetic amide F2α derivative ,it can selectively simulate the effect forefront amines produced by the body, which make aqueous humor production rate increase aqueous outflow resistance is reduced, by increasing the amount of aqueous outflow of the uveoscleral and trabecular Netcom channel to reduce intraocular pressure (IOP),it is considered to be the most effective hypotensive drug of topical ocular anti-glaucoma drugs,it is suitable for the treatment of open-angle glaucoma (POAG) or invalid elevated intraocular other ocular hypotensive medications compression syndrome (OHT) patients.
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