Neoprene is made from chloroprene (2-chloro-1,3-butadiene) as the main raw material α- Synthetic rubber produced by polymerization is widely used in anti-weathering products, viscose soles, coatings and rocket fuels.

Neoprene rubber is flexible and can maintain its shape over time, so it can be used to make padding for orthopedic support of wrist and knee. Laboratory personnel handling chemicals may use synthetic rubber gloves made of neoprene, which often have good flexibility, finger flexibility, high density and tear resistance to protect their hands from long-term chemical contact. Gloves made of neoprene can help protect the wearer's hands from hydraulic oil, gasoline, alcohol, organic acids and alkalis.